2H-Indol-2-one, 5,6-dichloro-1,3-dihydro- - Names and Identifiers
Name | 5,6-dichloro-1,3-dihydro-2H-indol-2-one
|
Synonyms | 5,6-Dichloro-2-oxindole 5,6-Dichloroindolin-2-one 5,6-DICHLOROINDOLIN-2-ONE 5,6-Dichloro-1,3-dihydroindol-2-one 5,6-dichloro-1,3-dihydro-2H-indol-2-one 5,6-Dichloro-1,3-dihydro-2H-indol-2-one 5,6-dichloro-2,3-dihydro-1H-indol-2-one 2H-indol-2-one, 5,6-dichloro-1,3-dihydro- 2H-Indol-2-one, 5,6-dichloro-1,3-dihydro-
|
CAS | 71293-59-9
|
InChI | InChI=1/C8H5Cl2NO/c9-5-1-4-2-8(12)11-7(4)3-6(5)10/h1,3H,2H2,(H,11,12) |
2H-Indol-2-one, 5,6-dichloro-1,3-dihydro- - Physico-chemical Properties
Molecular Formula | C8H5Cl2NO
|
Molar Mass | 202.04 |
Density | 1.497±0.06 g/cm3(Predicted) |
Melting Point | 209-210℃ |
Boling Point | 365.1±42.0 °C(Predicted) |
Flash Point | 174.633°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 12.19±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.615 |
2H-Indol-2-one, 5,6-dichloro-1,3-dihydro- - Introduction
5,6-dichloro-1,3-dihydro-2H-indol-2-one(5,6-dichloro-1,3-dihydro-2H-indol-2-one) is an organic compound. Its chemical formula is C8H5Cl2NO and its molecular weight is 208.04g/mol.
5,6-dichloro-1,3-dihydro-2H-indol-2-one is a solid crystal with a white crystalline appearance. It is insoluble in most organic solvents, but soluble in benzene and dichloromethane. This compound is relatively stable under conventional laboratory conditions.
5,6-dichloro-1,3-dihydro-2H-indol-2-one has application value in the field of medicine and pesticide. One of its main uses is as a pharmaceutical intermediate. In addition, it can also be used to synthesize key intermediates of pesticides.
Regarding the preparation method, a common synthesis method is to react indolone with a hydrofluoric acid solution in dichloromethane to generate 5,6-dichloro-1,3-dihydro-2H-indol-2-one. This reaction generally needs to be carried out at low temperatures and requires appropriate handling and purification steps.
For safety information, 5,6-dichloro-1,3-dihydro-2H-indol-2-one is less toxic and dangerous. However, any chemical should be used and stored with caution. When using 5,6-dichloro-1,3-dihydro-2H-indol-2-one, follow appropriate laboratory operating procedures and follow relevant laboratory safety guidelines. At the same time, contact with skin, eyes and respiratory tract must be avoided and ingestion avoided. When using this compound, pay attention to personal protective measures, such as wearing appropriate protective glasses, gloves and laboratory coats. In case of accidental contact, rinse immediately with plenty of water and seek medical help. Local and national laws and regulations shall be followed in the treatment and disposal of waste.
Last Update:2024-04-09 21:49:45